WEST LAFAYETTE, Ind. — The idea of the Ebola virus becoming airborne is not far-fetched and its ability to enter cells that line the trachea and lungs has been shown under controlled laboratory conditions, a Purdue University virus expert says.
David Sanders, an associate professor of biological sciences who has studied the Zaire strain of Ebola virus that is responsible for the current outbreak in West Africa, says the possibility of the virus becoming airborne should not be discounted.
A research team led by Sanders and collaborators from the University of Iowa established that the Zaire strain of Ebola virus could enter the epithelial cells that line the human airway in a paper published in the Journal of Virology in 2003. The experiment used a pseudotyped virus, which was built with the Ebola virus envelope proteins, or outer shell. The inside of the virus was that of a retrovirus to prevent replication of the Ebola virus and to more easily separate the functions of the outer and inner portions of the virus, he said.


